As Week 10 ushers in the second half of the NFL season, the stakes are climbing, and the playoff picture is starting to take shape. Fans of contending teams are beginning to envision a path to the Super Bowl, while others have shifted focus to next year’s draft, hoping to rebuild for a brighter future. With the competition intensifying, each game now has a heightened sense of urgency, as teams strive to either secure their postseason spots or set the foundation for the seasons ahead.
Let’s see if we can find some betting value in the NFL Vegas odds for week 10.
Week 10 offers 14 matchups, packed with storylines and pivotal games. Fans can look forward to key tests among playoff contenders, intense divisional face-offs, and an international clash in Germany featuring two struggling teams, the 2-7 New York Giants and the 2-7 Carolina Panthers.
Kicking things off on Thursday Night Football, the Cincinnati Bengals travel to Baltimore for an AFC North showdown against the Ravens, who come in as strong favorites, carrying over a touchdown advantage. The weekend highlight will undoubtedly be the Philadelphia Eagles squaring off against the Dallas Cowboys, reigniting one of football’s most storied rivalries.
Below are the odds for the match from three of the best Vegas NFL football betting sites.
| NFL Week 10 |  |  |  |
|---|---|---|---|
| Philadelphia Eagles | -360 | -360 | -360 |
| Dallas Cowboys | +280 | +290 | +290 |
| Eagles -7.5 | -110 | -110 | -110 |
| Cowboys +7.5 | -110 | -110 | -110 |
| Over 42.0 | -110 | -110 | -110 |
| Under 42.0 | -110 | -110 | -110 |
Both offenses are facing crucial absences, setting a challenging stage for this rivalry. Jalen Hurts might be without his top receiver A.J. Brown (knee) and reliable tight end Dallas Goedert (hamstring). Dallas is dealing with its own struggles, as Dak Prescott sits out with a hamstring injury, leaving CeeDee Lamb, nursing a sore shoulder, to play at less than 100 percent. With Prescott sidelined, Cooper Rush steps up, aiming to keep the Cowboys’ season alive.
Rush should bring some energy to the home crowd, but Philadelphia can look to Hurts and Saquon Barkley to keep things steady. A balanced ground game from the Eagles might be what they need to grind out a tough road win and secure another notch in this rivalry.
Eagles to edge this game. Dallas Cowboys +7.5 is -110 with BetOnline.
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The Bengals’ passing attack is thriving with Joe Burrow, who’s delivering MVP-caliber performances despite the team’s 4-5 record. Lamar Jackson, though, is equally impressive, playing like he’s intent on securing another MVP. Both teams have defenses with gaps that could lead to a high-scoring game. When it comes to versatility and a dependable power run game, Baltimore has a slight edge, especially with the home-field advantage in prime time. This late-game boost could make all the difference as the Ravens look to hold off the Bengals.
Ravens to win narrowly. Cincinnati Bengals +6 is -110 with BetOnline.
Daniel Jones continues to navigate the ups and downs of his role as the veteran starting quarterback for the Giants, regardless of New York’s outcomes. Meanwhile, Bryce Young seems to be showing enough flashes to earn himself a more extended opportunity into his second year with Carolina. In this overseas matchup, Jones is likely to face less pressure from Carolina’s pass rush than Young. With stronger receiving options and the benefit of his experience and athleticism, Jones should have the edge in this game.
Giants to win and cover the spread at odds of -108 with BetOnline.
See below, our partner table of the top sportsbooks where you can place your NFL week 10 bets.
