The 2025 Women’s March Madness tournament begins on Wednesday, March 19, with the First Four games. The annual basketball tournament wraps up with the crowning of the 2025 national champions on Sunday, April 6. The 2025 national championship game takes place at Amalie Arena in Tampa, Florida. The defending champion South Carolina Gamecocks are the betting favorites to repeat. They will face competition from the likes of UConn and UCLA. We look at the best bets and predictions for the 2025 Women’s March Madness tournament.
Find the best NCAA Men’s March Madness odds here
| To Win 2025 Women's NCAA Basketball Championship |  |  |  |
|---|---|---|---|
| South Carolina | +250 | +240 | +234 |
| Connecticut | +255 | +275 | +250 |
| UCLA | +450 | +500 | +600 |
| Texas | +650 | +650 | +670 |
| USC | +700 | +650 | +780 |
| Notre Dame | +750 | +750 | +1000 |
| Duke | +3500 | +3300 | +3900 |
| NC State | +3500 | +15000 | +4900 |
| TCU | +3500 | +3300 | +3700 |
| LSU | +5000 | +4000 | +4500 |
| Baylor | +15000 | +15000 | +14000 |
| Kansas State | +15000 | +15000 | +9000 |
| Kentucky | +15000 | +15000 | +14000 |
| Mississippi | +15000 | +15000 | +17000 |
| North Carolina | +15000 | +15000 | +19000 |
| Ohio State | +15000 | +15000 | +15000 |
| Oklahoma | +15000 | +20000 | +12000 |
| Maryland | +17500 | +17500 | +22000 |
| Tennessee | +17500 | +17500 | +13000 |
The South Carolina Gamecocks bring a 30-3 record with them into the 2025 NCAA tournament. The defending national champions were 22-1 to open the year. The team’s only loss between November 4 and February 6 came on November 24 when the UCLA Bruins beat them 77-62 on UCLA’s home court. South Carolina went 1-2 in mid-February, beating Florida, but losing to Texas (66-62) and UConn (87-58) during that stretch. The team is on a seven-game winning streak headed into March Madness.
The Gamecocks were undefeated heading into the past two NCAA tournaments. The team is the dominant force in women’s college basketball, winning the national title in two of the past three years.
South Carolina plays a solid team-based game. They were ranked fifth in scoring offense (80.5 PPG) in the SEC and second in scoring defense (57.8 PPG) this year.
The Gamecocks face Tennessee Tech in their first March Madness game.
UConn won four straight national championships between 2013 and 2016. The team has only made the finals once since then, losing to South Carolina (64-49) in 2022. The Huskies look to get back to the NCAA championship on the strength of a 31-3 season. UConn were the No. 1 team in the Big East.
Injuries have cost the Huskies over the past few years, but the team is healthy and deep heading into March Madness. UConn has made the Final Four in 15 of the past 16 March Madness tournies.
UConn has a solid core in senior Paige Bueckers, who is expected to be the first pick in the upcoming WNBA draft, along with Azzi Fudd, and Sarah Strong. Bueckers has helped the team make the Final Four in each year she has played, but she does not have a national title to her name.
The Huskies open the tournament against the No. 15 seeded Arkansas State.
The UCLA Bruins had their first 30-win season in team history in 2025, going 30-2, while also picking up their first No. 1 ranking in the AP poll. The Bruins would hold that ranking for 12 straight weeks. The team was the No. 2 club in the Big Ten and finished the year by avenging their two losses to USC (71-60, 80-67) with a 72-67 win in the Big Ten tournament final. UCLA defeated South Carolina in November by a score of 77-62.
The Bruins are looking to at least make the Final Four after falling in the Sweet 16 in the past two years. UCLA is incredibly deep this year, with players like Lauren Betts and Kiki Rice leading the way. Seven Bruins’ players are averaging at least seven points per game heading into March Madness. That team depth should serve the Bruins well and could be a key to a long tournament run for UCLA in 2025.
The Bruins open March Madness with a first-round game against the winner of the UC San Diego vs. Southern University game.
South Carolina has all the tools to win back-to-back national championships. Especially noteworthy is the team’s bench, which is averaging an astounding 41.5 points per game.
The betting pick is that the South Carolina Gamecocks will win the 2025 women’s national championship.
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