This weekend, National Football League fans are going to be treated to some epic showdowns, as Week 6 has arrived already. Week 5 provided plenty of drama, as we saw some back-and-forth matchups. In this article, we have NFL Week 6 picks for the 2022 season. This includes the big-time matchup between the Bills and Chiefs. Who will come out on top?
Heading into the weekend, the Bills are slight favorites over the Chiefs in what is no question the biggest matchup of the season thus far. Both Buffalo and Kansas City have title aspirations, as they both have fantastic Super Bowl betting odds. Those odds are only going to keep growing with how impressive the two squads have looked, especially on offense.
Starting with the Bills, Josh Allen has looked superb running the O for the AFC East side and he’s 100 percent in the MVP conversation. What’s holding the Bills back a bit has been the running game, but the latest rumors around NFL circles suggest the team could try and trade for Christian McCaffrey. If this goes down, then Buffalo will really be a team to watch in the postseason.
| NFL Week 6 |  |  |  |  |
|---|---|---|---|---|
| Bills to win | -125 | -125 | -125 | -125 |
| Chiefs to win | +145 | +145 | +145 | +145 |
| Ravens to win | -230 | -230 | -230 | -230 |
| Giants to win | +190 | +190 | +190 | +190 |
As for Kansas City, they’re fresh off their thrilling Monday Night Football win over the Las Vegas Raiders. Patrick Mahomes – what else is there to say about this kid? He continues to dazzle and he tossed four touchdowns on MNF to star tight end Travis Kelce. Kelce continues to be the best tight end in all of football and he’s never going to have to pay for a beer in KC again.
According to the best-rated sportsbooks, which includes the reliable Bovada review, the Bills are -125 favorites to take down the Chiefs at Arrowhead. Kansas City has been placed at +145. This is going to be a battle and a high-scoring affair. At the end of the day, we think the Chiefs won’t be able to get the job done. We’re going with Buffalo as our pick to win.
In another fun matchup, Baltimore will take down the Giants at MetLife Stadium on Sunday afternoon. This is going to be a good one, as the Ravens are 3-2 on the year, while the G-Men improved to 4-1 following their stunning upset win over the Packers in London at the Tottenham Hotspur Stadium. No one thought the Giants would pull that off, but they did.
With Baltimore, this team was against the ropes going up against the Cincinnati Bengals on Sunday Night Football, with Joe Burrow looking like he was going to lead Cincy to a big win. However, Lamar Jackson drove down the field late and Justin Tucker, the best kicker in the game, drilled a field goal as time expired to lift the Ravens to a memorable victory.
With the Giants, no one expected them to be 4-1 at this point in the year. They were 8.5-point underdogs going up against the Packers in England, but Daniel Jones and Saquon Barkley pulled this one off out of their hats. New York continues to stun people each weekend and they’re only a few plays away from being 5-0. Do they have what it takes to pull off yet another huge win?
Per the oddsmakers, the Ravens hold -230 odds, while the Giants have been placed at +190. The G-Men are hoping they can pull another rabbit out of their hat, but slowing down Jackson is no easy task. The Giants defense has been strong, but they could be in for a long day. We like Baltimore in this one. We’re going with the Ravens. Agree? Check out our NFL betting sites to get a wager in.
Over in Green Bay, the Packers will bounce back vs. the Jets. Aaron Rodgers and this offense is in desperate need of a big game and luckily, the Jets are one of the worst teams in the game. Their defense leaves a lot to be desired too, which will be good news for Rodgers and running back Aaron Jones. With Green Bay, they’ve simply got to find a way to establish the run.
Rodgers tossed for two touchdowns in the first half vs. the Giants on Sunday, but they contained him in the second half. Rather than focus on the ground game, the Packers kept the ball out of Jones hands and fans were furious with that thinking.
Jones is one of the best RBs in the NFC and this team needs to feed him the rock. Green Bay enters this one with -355 odds, and the Jets are at +270. Lambeau Field will be packed and they’ll be treated with a big win for GB and Rodgers. We’re rocking with the Packers as our pick. Look for Rodgers to throw for north of 300 yards, while Jones should score at least one touchdown.
